Since Lucy was away this week, I decided to do more of a documentary format with the show, looking at the history of Andrew Wakefield’s involvement in the genesis of the anti-vaccine movement. This is not supposed to be a rebuttal of the anti-vaccine movement, it is not meant to be a defence of vaccines. I do not go into studies that disprove the claims against vaccines, this is merely a look at the controversy that began the push against vaccines, and how it holds up (or doesn’t) against scrutiny, both from the scientific community, or even itself.
MMR: What they didn’t tell you – Brian Deer documentary on Andrew Wakefield
The Lancet Scandal – Page one of a three page dossier outlining documentation and sources for Wakefield’s activities.
Wakefield’s Smoking Gun – A brilliant video outlining the problems with Wakefield’s 2002 study claiming to have found live measles virus in the guts of children who have received the MMR vaccine.
UK Patent GB 2 325 856 A
UK Patent GB 2 341 551 A
UK Patent GB 2 347 742 A
Wakefield, A. J., Pittilo, R. M., Sim, R., Cosby, S. L., Stephenson, J. R., Dhillon, A. P. and Pounder, R. E. (1993), Evidence of persistent measles virus infection in Crohn’s disease. J. Med. Virol., 39: 345–353. doi:10.1002/jmv.1890390415
Thompson, N., Montgomery, S., Pounder, R. & Wakefield, a. Is measles vaccination a risk factor for inflammatory bowel disease? Lancet 345, 1071–1074 (1995).
The Independent (Law, Page 25) November 27 1996
Comparison of when the children entered into the lawsuit vs when they were admitted to Royal Free for the study
The Wakefield deal with Dawbarns – Audio files from Barr, Horton, and Walker-Smith at the bottom
Hugh Fudenberg (Wikipedia)
Hugh Fudenberg disciplinary action
Wakefield, A. et al. RETRACTED: Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children. Lancet 351, 637–641 (1998).
Letter of concern and response to The Lancet regarding Wakefield’s involvement in the lawsuit
Wakefield’s letter to The Lancet in response to the partial retraction of his 1998 article
Payments made to various expert witnesses during the class action lawsuit. Wakefield is second from the top.
Wakefield, A. J. et al. Enterocolitis in children with developmental disorders. Am J Gastroenterol 95, 2285–2295 (2000).
Uhlmann, V. et al. Potential viral pathogenic mechanism for new variant inflammatory bowel disease. J Clin Pathol Mol Pathol 55, 84–90 (2002).
Dr Chadwick’s results from the MMR study
Wakefield’s response to allegations he omitted the negative test results from the original study
Alternate link to the same statement on a site white is more sympathetic to Wakefield